• Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis 

      Becker-Merok, Andrea; Kalaaji, Manar; Haugbro, Kaia; Nikolaisen, Cathrin; Nilsen, Kirsten; Rekvig, Ole Petter; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-10-24)
      This study investigated the overall clinical impact of anti-α- actinin antibodies in patients with pre-selected autoimmune diseases and in a random group of anti-nuclear antibody (ANA)- positive individuals. The relation of anti-α-actinin antibodies with lupus nephritis and anti-double-stranded DNA (anti-dsDNA) antibodies represented a particular focus for the study. Using a cross-sectional ...
    • Diagnostic value of antibodies against mutated citrullinated vimentin for rheumatoid arthritis 

      Besada, Emilio; Nikolaisen, Cathrin; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      OBJECTIVES: To compare the diagnostic efficiency of anti-MCV, anti-CCP2 and RF detection for patients with RA. METHODS: Cross-sectional study of patients with established rheumatic disease: rheumatoid arthritis (RA; n=75), psoriatic arthritis (PsA; n=25), 27 patients with ankylosing spondylitis (AS; n=27) and connective tissue disease (CTD; n=17). Anti-CCP2, anti-MCV and RF were detected by ...
    • Should rheumatoid factor in rheumatoid arthritis be sent to Davy Jones's Locker? 

      Besada, Emilio; Nikolaisen, Cathrin; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      This article reviews the characteristics and weaknesses of the rheumatoid factor (RF) assay compared with anticitrullinated peptide antibody (ACPA) testing in the work-up of patients with synovitis. This should lead physicians to change their ordering habits and replace RF by ACPA. For RA diagnosis, good clinical judgement based on clinical history, physical examination and routine laboratory work ...